Template:On this day - April 16

Charles I of Spain

• 69 – Death of Otho, Roman emperor (b. 32).
• 1503 – Christopher Columbus returns to Spain from his fourth and last voyage, abandoning Santa María de Belén, on the coast of Veraguas (Panama).
• 1519 – In Barcelona, Charles I of Spain is sworn before the Cortes of Barcelona, together with his mother Joanna the Mad.
• 1531 – In Mexico, the village of Puebla de los Ángeles (the present-day city of Puebla) is founded.
• 1566 – Death of Juan Correa de Vivar, Spanish Renaissance painter (b. 1510).
• 1568 – In Granada (Spain), the Moriscos rise up in arms in opposition to the measures adopted by Pedro Deza, president of the Chancery of Granada.
• 1582 – In the north of present-day Argentina (in the south of the former Viceroyalty of Peru), the Spanish conquistador Hernando de Lerma founds the town of Salta.
• 1610 – Lope de Vega signs and dates his play La encomienda bien guardada.
• 1812 – In Hontoria de Valdearados, in the south of the Province of Burgos (Spain), the guerrillas of the priest Merino capture the 1st battalion of the Vistula Regiment.
• 1828 – Death of Francisco de Goya, Spanish painter and illustrator (b. 1746).
• 1838 – The Pastry War begins between Mexico and France.
• 1850 – In Chile, the port city of Huasco is founded.
• 1880 – In Spain, the Círculo de Bellas Artes of Madrid is constituted.
• 1910 – In Colombia, the department of Valle del Cauca is founded.
• 1911 – In the State of Puebla (Mexico), Jesús Morales "El Tuerto" takes part in the attacks on Chietla and in the capture of Izúcar de Matamoros, as well as in the taking of the spinning and weaving mill of Metepec.
• 1943 – Death of Carlos Arniches, Spanish comic playwright of the Generation of '98 (b. 1866).
• 1961 – In Havana (Cuba), the victims of the bombings of Cuban airports by U.S. mercenary planes are buried.
• 1973 – Nino Bravo, Spanish singer of romantic ballad and baroque pop, dies in a traffic accident (b. 1944).
• 1987 – In Argentina, the first of the Carapintada uprisings begins.
• 2016 – In Ecuador, an earthquake of 7.8 on the Richter scale, with its epicenter in Esmeraldas, leaves 670 dead.
• 2020 – Death of Luis Sepúlveda, Chilean writer and film director (b. 1949).